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Jonathan Byrne

Jonathan Byrne
Consultant Cardiologist


Dr Jonathan Byrne is an interventional cardiologist who specialises in the treatment of coronary artery disease. This involves the treatment of patients with angina, heart failure, heart rhythm disturbances and high blood pressure.


A large part of Dr. Byrne's practice is concerned with the treatment of coronary artery disease including angioplasty and stent procedures. He also treats patients with valvular heart disease with new treatments which do not require an operation, such as TAVI (transcatheter aortic valve implantation) and Mitraclip (percutaneous treatment of the mitral valve). Dr Byrne performs a number of imaging tests for the heart including transoesophageal echocardiography and cardiac CT scanning.


Dr Byrne completed his undergraduate medical training in Bristol and then continued general professional medical training in the South-East of England and London. He then undertook a PhD in the academic department of Cardiology at King’s College Hospital examining molecular mechanisms underlying left ventricular hypertrophy. Following completion of his PhD Dr Byrne undertook specialist training in Cardiology on the South Thames rotation.


He continued his training in interventional cardiology at King’s College Hospital from 2004, and on Vancouver Island as a Boston scientific sponsored Interventional Fellow. Following his return to the UK in 2007 Dr Byrne completed his training in interventional cardiology, talong with transoeophageal echocardiography and cardiac CT scanning

    Clinical interests

  • Dr Byrne's general cardiology interests include the assessment and treatment of coronary and valvular heart disease and risk stratification. He also treats hypertension and general heart rhythm disturbances, with interventional, catheter-based treatment of artery or valve disease forming the mainstay of his clinical practice. This includes the treatment of narrowed, diseased heart arteries with angioplasty and stents, the majority of procedures being performed through the wrist.

    As well as percutaneous coronary intervention, Dr Byrne‚Äôs clinical interests also include transoesophageal echocardiography and cardiac CT. He has been involved in the development of the structural programme at Kings College Hospital, with the use of novel percutaneous techniques to treat aortic (TAVI) and mitral valve disease. 

    Key procedures

    • Percutaneous coronary intervention: 350 procedures / year
    • Coronary angiograms: 500+ / year
    • Transcatheter aortic valve implants: 40 / year

    Dr Byrne reported 350 procedures in the year 2011 with a complication rate of less than 1% for elective procedures.

    Research interests

  • Dr Byrne's research interests have included the molecular mechanisms which underlie the development of left ventricular hypertrophy, and the application of coronary physiology in an interventional setting. His research has also explored the differences and potential advantages of intervention performed from the radial artery in the wrist.  

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